Items where Author is "Gerhard, U."
Number of items: 21.
Article
NK1 antagonists based on seven membered lactam scaffolds. (2006)
J. M. Elliott,
E. J. Carlson,
G. G. Chcchi,
O. Dirat,
M. Dominguez,
U. Gerhard,
R. Jelley,
A. B. Jones,
M. M. Kurtz,
K. I. Tsao
and
A. Wheeldon
A New Pyridazine Series of GABAA α5 Ligands. (2005)
M.B. Van Niel,
K. Wilson,
C.H. Adkins,
J.R. Atack,
J.L. Castro,
D.E. Clarke,
S. Fletcher,
U. Gerhard,
M.M. Mackey,
S. Malpas,
K. Maubach,
R. Newman,
D. O'Connor,
G.V. Pillai,
P.B. Simpson,
S.R. Thomas
and
A.M. MacLeod
H-1 NMR study of the conformation and absolute stereochemistry of two spirocyclic NK-1 antagonists. (2005)
R. H. Herbert,
U. Gerhard,
R. J. Mortishire-Smith,
S. R. Thomas
and
G. Hollingworth
Aryl sulfones : A new class of γ-secretase inhibitors. (2005)
M. Teall,
P. Oakley,
T. Harrison,
D. Shaw,
E. Kay,
J. Elliott,
U. Gerhard,
J.L. Castro,
M. Shearman,
R.G. Ball
and
N.N. Tsou
Accelerated metabolite identification by "Extraction-NMR". (2003)
U. Gerhard,
S. Thomas
and
R. Mortishire-Smith
Metabolite identification in drug discovery. (2003)
A.P. Watt,
R.J. Mortishire-Smith,
U. Gerhard
and
S.R. Thomas
Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring. (2002)
K.R. Gibson,
L. Hitzel,
R.J. Mortishire-Smith,
U. Gerhard,
R.A. Jelley,
A.J. Reeve,
M. Rowley,
A. Nadin
and
A.P. Owens
Identification of metabolites of a substance P (Neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma. (2002)
C.E.C.A. Hop,
Y. Wang,
S. Kumar,
M.V.S. Elipe,
C.E. Raab,
D.C. Dean,
G.K. Poon,
C.-A. Keohane,
J. Strauss,
S.-H.L. Chiu,
N. Curtis,
J. Elliott,
U. Gerhard,
K. Locker,
D. Morrison,
R. Mortishire-Smith,
S. Thomas,
A.P. Watt
and
D.C. Evans
Neighboring group participation of the indole nucleus : An unusual DAST-mediated rearrangerment reaction. (2000)
D.J. Hallett,
U. Gerhard,
S.C. Goodacre,
L. Hitzel,
T.J. Sparey,
S. Thomas,
M. Rowley
and
R.G. Ball
Aromatic compounds from the liverwort Plagiochila spinulosa. (1999)
D.S. Rycroft,
D.L. Srivastava,
W.J. Cole,
P. Ifeadike,
S.F. Kimbu,
J. Singh,
J.D. Connolly,
C. Thom,
U. Gerhard,
A.J. Organ,
R.J. Smith,
M. Hughes
and
L.J. Harrison
Synthesis of conformationally constrained analogues of BRL32872 : Determination of stereochemistry and related pharmacological properties. (1997)
M. Souchet,
M.-C. Forest,
B. Cheval,
S. Rouanet,
J.-F. Faivre,
A. Bril,
U. Gerhard
and
R.J. Smith
Two conformers of the glycopeptide antibiotic teicoplanin with distinct ligand binding sites. (1995)
M.S. Westwell,
U. Gerhard
and
D.H. Williams
Dissection of the contributions toward dimerization of glycopeptide antibiotics. (1994)
J.P. Mackay,
U. Gerhard,
D.A. Beauregard,
R.A. Maplestone
and
D.H. Williams
Glycopeptide antibiotic activity and the possible role of dimerization : A model for biological signaling. (1994)
J.P. Mackay,
U. Gerhard,
D.A. Beauregard,
M.S. Westwell,
M.S. Searle
and
D.H. Williams
Rational design and binding of modified cell-wall peptides to vancomycin-group antibiotics : Factorising free energy contributions to binding. (1993)
S.E. Holroyd,
P. Groves,
M.S. Searle,
U. Gerhard
and
D.H. Williams
Toward an estimation of binding constants in aqueous solution : Studies of associations of vancomycin group antibiotics. (1993)
D.H. Williams,
M.S. Searle,
J.P. Mackay,
U. Gerhard
and
R.A. Maplestone
The free energy change of restricting a bond rotation in the binding of peptide analogues to vancomycin group antibiotics. (1993)
U. Gerhard,
M.S. Searle
and
D.H. Williams
The role of the sugar and chlorine substituents in the dimerization of vancomycin antibiotics. (1993)
U. Gerhard,
J.P. Mackay,
R.A. Maplestone
and
D.H. Williams
Partitioning of free energy contributions in the estimation of binding constants : Residual motions and consequences for amide-amide hydrogen bond strengths. (1992)
M.S. Searle,
D.H. Williams
and
U. Gerhard
Toward the semiquantitave estimation of binding constants : Guides for peptide-peptide binding in aqueous solution. (1991)
D.H. Williams,
J.P.L. Coxs,
A.J. Doig,
M. Gardner,
U. Gerhard,
P.T. Kaye,
A.R. Lal,
I.A. Nicholls,
C.J. Salter
and
R.C. Mitchell
Other
Identification of metabolites of a substance P (NK1 receptor) antagonist in rat hepatocytes and rat plasma. (2002)
C.E.C.A. Hop,
Y. Wang,
S. Kumar,
M.V.S. Elipe,
C.E. Raab,
D.C. Dean,
G.K. Poon,
C.-A. Keohane,
J. Strauss,
S.-H.L. Chiu,
N. Curtis,
J. Elliott,
U. Gerhard,
K. Locker,
D. Morrison,
R. Mortishire-Smith,
A.P. Watt
and
D.C. Evans