Author
Number of items: 28.
2015
  • The Khat and Meow Meow Tale : Teaching the Relevance of Chemistry through Novel Recreational Drugs. (2015) Suzanne Fergus, Kathryn Kellett and Ute Gerhard
    • 2006
  • NK1 antagonists based on seven membered lactam scaffolds. (2006) J. M. Elliott, E. J. Carlson, G. G. Chcchi, O. Dirat, M. Dominguez, U. Gerhard, R. Jelley, A. B. Jones, M. M. Kurtz, K. I. Tsao and A. Wheeldon
    • 2005
  • A New Pyridazine Series of GABAA α5 Ligands. (2005) M.B. Van Niel, K. Wilson, C.H. Adkins, J.R. Atack, J.L. Castro, D.E. Clarke, S. Fletcher, U. Gerhard, M.M. Mackey, S. Malpas, K. Maubach, R. Newman, D. O'Connor, G.V. Pillai, P.B. Simpson, S.R. Thomas and A.M. MacLeod
  • Aryl sulfones : A new class of γ-secretase inhibitors. (2005) M. Teall, P. Oakley, T. Harrison, D. Shaw, E. Kay, J. Elliott, U. Gerhard, J.L. Castro, M. Shearman, R.G. Ball and N.N. Tsou
  • Fractionlynx for mass directed purification of metabolites : an alternative tool to get a metabolite into a NMR magnet. (2005) David Gunn, Jenny Kingston, S R Thomas, R J Mortishire-Smith and Ute Gerhard
  • H-1 NMR study of the conformation and absolute stereochemistry of two spirocyclic NK-1 antagonists. (2005) R. H. Herbert, U. Gerhard, R. J. Mortishire-Smith, S. R. Thomas and G. Hollingworth
    • 2004
  • Open-access high-resolution mass spectrometry in early drug discovery. (2004) S. R. Thomas and Ute Gerhard
    • 2003
  • Metabolite identification in drug discovery. (2003) A.P. Watt, R.J. Mortishire-Smith, U. Gerhard and S.R. Thomas
  • Accelerated metabolite identification by "Extraction-NMR". (2003) U. Gerhard, S. Thomas and R. Mortishire-Smith
    • 2002
  • Identification of metabolites of a substance P (Neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma. (2002) C.E.C.A. Hop, Y. Wang, S. Kumar, M.V.S. Elipe, C.E. Raab, D.C. Dean, G.K. Poon, C.-A. Keohane, J. Strauss, S.-H.L. Chiu, N. Curtis, J. Elliott, U. Gerhard, K. Locker, D. Morrison, R. Mortishire-Smith, S. Thomas, A.P. Watt and D.C. Evans
  • Synthesis and conformational dynamics of tricyclic pyridones containing a fused seven-membered ring. (2002) K.R. Gibson, L. Hitzel, R.J. Mortishire-Smith, U. Gerhard, R.A. Jelley, A.J. Reeve, M. Rowley, A. Nadin and A.P. Owens
  • Identification of metabolites of a substance P (NK1 receptor) antagonist in rat hepatocytes and rat plasma. (2002) C.E.C.A. Hop, Y. Wang, S. Kumar, M.V.S. Elipe, C.E. Raab, D.C. Dean, G.K. Poon, C.-A. Keohane, J. Strauss, S.-H.L. Chiu, N. Curtis, J. Elliott, U. Gerhard, K. Locker, D. Morrison, R. Mortishire-Smith, A.P. Watt and D.C. Evans
    • 2000
  • Neighboring group participation of the indole nucleus : An unusual DAST-mediated rearrangerment reaction. (2000) D.J. Hallett, U. Gerhard, S.C. Goodacre, L. Hitzel, T.J. Sparey, S. Thomas, M. Rowley and R.G. Ball
    • 1999
  • Aromatic compounds from the liverwort Plagiochila spinulosa. (1999) D.S. Rycroft, D.L. Srivastava, W.J. Cole, P. Ifeadike, S.F. Kimbu, J. Singh, J.D. Connolly, C. Thom, U. Gerhard, A.J. Organ, R.J. Smith, M. Hughes and L.J. Harrison
  • Neighbouring Group Participation of the Indole Nucleus : An Unusual DAST Mediated Rearrangement Reaction Monitored by Low Temperature NMR Spectroscopy. (1999) Ute Gerhard, S.C. Goodacre, D.J. Hallett, M. Rowley, T.J. Sparey and S R Thomas
    • 1997
  • Synthesis of conformationally constrained analogues of BRL32872 : Determination of stereochemistry and related pharmacological properties. (1997) M. Souchet, M.-C. Forest, B. Cheval, S. Rouanet, J.-F. Faivre, A. Bril, U. Gerhard and R.J. Smith
    • 1995
  • Two conformers of the glycopeptide antibiotic teicoplanin with distinct ligand binding sites. (1995) M.S. Westwell, U. Gerhard and D.H. Williams
  • Ligands which bind weakly to vancomycin : Studies by 13C NMR spectroscopy. (1995) C.M. Pearce, D.H. Williams and Ute Gerhard
  • Optimisation of a Non-Commercial Loop-Storage Unit and Comparison with Continuous-Flow and Stopped-Flow Experiments in LC-NMR. (1995) Nigel J. Bailey, Eleanor A. Crowe, Ute Gerhard and John K. Roberts
    • 1994
  • Dissection of the contributions toward dimerization of glycopeptide antibiotics. (1994) J.P. Mackay, U. Gerhard, D.A. Beauregard, R.A. Maplestone and D.H. Williams
  • Glycopeptide antibiotic activity and the possible role of dimerization : A model for biological signaling. (1994) J.P. Mackay, U. Gerhard, D.A. Beauregard, M.S. Westwell, M.S. Searle and D.H. Williams
    • 1993
  • Toward an estimation of binding constants in aqueous solution : Studies of associations of vancomycin group antibiotics. (1993) D.H. Williams, M.S. Searle, J.P. Mackay, U. Gerhard and R.A. Maplestone
  • Rational design and binding of modified cell-wall peptides to vancomycin-group antibiotics : Factorising free energy contributions to binding. (1993) S.E. Holroyd, P. Groves, M.S. Searle, U. Gerhard and D.H. Williams
  • The free energy change of restricting a bond rotation in the binding of peptide analogues to vancomycin group antibiotics. (1993) U. Gerhard, M.S. Searle and D.H. Williams
  • The role of the sugar and chlorine substituents in the dimerization of vancomycin antibiotics. (1993) U. Gerhard, J.P. Mackay, R.A. Maplestone and D.H. Williams
    • 1992
  • Partitioning of free energy contributions in the estimation of binding constants : Residual motions and consequences for amide-amide hydrogen bond strengths. (1992) M.S. Searle, D.H. Williams and U. Gerhard
    • 1991
  • Toward the semiquantitave estimation of binding constants : Guides for peptide-peptide binding in aqueous solution. (1991) D.H. Williams, J.P.L. Coxs, A.J. Doig, M. Gardner, U. Gerhard, P.T. Kaye, A.R. Lal, I.A. Nicholls, C.J. Salter and R.C. Mitchell
    • 1989
  • The fragmentation behaviour of alkylated thiophene-1,1-dioxides. (1989) Herbert Budzikiewicz and Ute Gerhard