Author
Number of items: 50.
The non-genomic effects of the PPARβγ agonist GW0742 on streptozotocin treated rat aorta. (2018)
Noelia Perez-Diaz,
Igor Pushkarsky,
Nadia Oweis,
Lisa Lione
and
Louise S Mackenzie
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Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies. (2016)
Yousif Shamsaldeen,
Louise MacKenzie,
Lisa Lione
and
Christopher Benham
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A New NO-Releasing Nanoformulation for the Treatment of Pulmonary Arterial Hypertension. (2016)
Nura A. Mohamed,
Blerina Ahmetaj-Shala,
Lucie Duluc,
Louise S. Mackenzie,
Nicholas S. Kirkby,
Daniel M. Reed,
Paul D. Lickiss,
Robert P. Davies,
Gemma R. Freeman,
Beata Wojciak-Stothard,
Adrian H. Chester,
Ibrahim M. El-Sherbiny,
Jane A. Mitchell
and
Magdi H. Yacoub
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Evidence that Diclofenac and Celecoxib are thyroid hormone receptor beta antagonists. (2016)
Mire Zloh,
Noelia Perez Diaz,
Leslie Tang,
Pryank Patel
and
Louise Susan MacKenzie
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In silico modelling of prostacyclin and other lipid mediators to nuclear receptors reveal novel thyroid hormone beta receptor antagonist properties. (2016)
Noelia Perez Diaz,
Mire Zloh,
Pryank Patel
and
Louise Susan MacKenzie
Reply to Letter Regarding Article, "Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine : Novel Explanation of Cardiovascular Side Effects Associated With Anti-Inflammatory Drugs". (2015)
Blerina Ahmetaj-Shala,
Nicholas S. Kirkby,
Rebecca Knowles,
Malak Al'Yamani,
Sara Mazi,
Zhen Wang,
Arthur T. Tucker,
Louise Susan Mackenzie,
Paul C. J. Armstrong,
Rolf M. Nüsing,
James A. P. Tomlinson,
Timothy D. Warner,
James Leiper
and
Jane A. Mitchell
Evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine : novel explanation of cardiovascular side effects associated with anti-inflammatory drugs. (2015)
Blerina Ahmetaj-Shala,
Nicholas S. Kirkby,
Rebecca Knowles,
Malak Al'Yamani,
Sarah Mazi,
Zhen Wang,
Arthur T. Tucker,
Louise Mackenzie,
Paul C. J. Armstrong,
Rolf M. Nüsing,
James A. P. Tomlinson,
Timothy D. Warner,
James Leiper
and
Jane A. Mitchell
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Linking Induction and Transrepression of PPARβ/δ with Cellular Function. (2015)
Noelia Perez Diaz
and
Louise Susan MacKenzie
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Role of prostacyclin in pulmonary hypertension. (2014)
Jane A. Mitchell,
Blerina Ahmetaj-Shala,
Nick Kirkby,
William R. Wright,
Louise Susan MacKenzie,
Dan Reed
and
Nura Mohamed
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The PPARβ/δ agonist GW0742 prevents LPS-induced nitrite production in rat parenchyma but not in aorta or pulmonary arteries. (2014)
Noelia Perez Diaz,
Jehan Barakat,
Fernando Perez-Vizcaino,
Laura Moreno
and
Louise Susan MacKenzie
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Selective inhibition of NADPH Oxidase reverses the over contraction of diabetic rat aorta. (2014)
Atif ur Rehman,
Elma Dugic,
Christopher Benham,
Lisa Lione
and
Louise Susan MacKenzie
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Harnessing the benefits of PPARβ/δ agonists. (2013)
Louise Susan MacKenzie
and
Lisa Lione
Linking Phospholipase C isoforms with differentiation function in human vascular smooth muscle cells. (2013)
Louise Susan MacKenzie,
Joanne Lymn
and
Alun D. Hughes
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Aspirin triggered 15-epi-lipoxin A4 predicts cyclo-oxygenase-2 in the lungs of LPS treated mice but not in the circulation : implications for a clinical test. (2013)
Nick Kirkby,
M.V. Chan,
M.H. Lundberg,
Louise MacKenzie,
Phillip D.M. Leadbeater,
Ginger L. Milne,
Claire M. Potter,
Malak Al-Yamani,
Oladipupo Adeyemi,
Tim D. Warner
and
Jane A. Mitchell
NADPH oxidase is the source of ROS in STZ rat aorta : use of the novel highly selective NOX inhibitor VAS2870. (2013)
Elma Dugic,
Yousif Shamsaldeen,
Christopher David Benham
and
Louise MacKenzie
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LC-MS/MS Confirms That COX-1 Drives Vascular Prostacyclin Whilst Gene Expression Pattern Reveals Non-Vascular Sites of COX-2 Expression. (2013)
N.S. Kirkby,
A.K. Zaiss,
P. Urquhart,
J. Jiao,
P.J. Austin,
Malak Al-Yamani,
M.H. Lundberg,
Louise MacKenzie,
T.D. Warner,
A. Nicolaou,
H.R. Herschman
and
J.A. Mitchell
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Nitric oxide-dependent vasodilation is compromised in isolated pulmonary arteries from COX knockout mice. (2013)
Will Wright,
Louise Susan MacKenzie,
N.S. Kirkby
and
Jane A. Mitchell
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Cross-talk between toll-like receptor 4 (TLR4) and proteinase-activated receptor 2 (PAR) is involved in vascular function. (2013)
M. Bucci,
V. Vellecco,
V. Brancaleone,
F. Roviezzo,
G. Mattace Raso,
A. Ianaro,
R. Meli,
G. Cirino,
L. Harrington,
G. Lungarella
and
R. De Palma
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Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system. (2012)
N.S. Kirkby,
M.H. Lundberg,
L.S. Harrington,
P.D.M. Leadbeater,
C.M.F. Potter,
M. Al-Yamani,
O. Adeyemi,
J.A. Mitchell,
T.D. Warner
and
G.L. Milne
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Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia. (2012)
B. Wojciak-Stothard,
L. Zhao,
E. Oliver,
O. Dubois,
Y. Wu,
D. Kardassis,
E. Vasilaki,
J.A. Mitchell,
M. Huang,
Louise Susan MacKenzie,
G.C. Prendergast
and
M.R. Wilkins
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Role of the endothelium and COX-1 in prostacyclin generation by whole vessels stimulated with different agonists. (2012)
Malak Alyamanil,
N.S. Kirkby,
Louise Susan MacKenzie,
M.H. Lundberg,
T.D. Warner
and
J.A. Mitchell
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Contribution of COX1 and COX2 to prostacyclin release by healthy mouse tissues. (2011)
N.S. Kirkby,
Louise Harrington,
Martina Lundberg,
T. Hoefer,
Tim D. Warner
and
Jane A. Mitchell
Role of COX-1 and COX-2 in the release of prostanoids in murine lung and isolated lung fibroblasts. (2011)
William Wright,
Nick Kirkby,
Louise Susan MacKenzie,
Martina Lundberg,
M.J. Paul-Clark
and
T.D. Warner
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Reduced endothelial dependent vasodilation in vessels from TLR4 mice is associated with increased superoxide generation. (2011)
L.S. Harrington,
M.H. Lundberg,
M. Waight,
A. Rozario
and
J.A. Mitchell
Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms. (2011)
C.M.F. Potter,
M.H. Lundberg,
L.S. Harrington,
A.V. Moshkov,
J. Gorelik,
J.A. Mitchell,
C.M. Warboys,
P.D. Weinberg,
T.D. Warner
and
R.E. Berson
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Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells : Comparison with Toll-like receptor 4 responses in macrophages. (2010)
L. Moreno,
S.K. McMaster,
T. Gatheral,
L. Bailey,
L. Harrington,
N. Cartwright,
P.C.J. Armstrong,
T.D. Warner,
M. Paul-Clark
and
J.A. Mitchell
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Making anti-thrombotic bypass vessels from selected populations of vascular smooth muscle cells. (2010)
A.A. Dhanji,
F.Y. Ali,
Louise Susan MacKenzie,
A. Shipolini,
J.A. Mitchell
and
T.D. Warner
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The PPARβ/δagonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension. (2010)
L.S. Harrington,
L. Moreno,
A. Reed,
J.A. Mitchell,
S.J. Wort,
B. Desvergne,
C. Garland
and
L. Zhao
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COX-1 or COX-2 deletion is associated with increased nuclear NF-κB in the endothelium of the aortic arch. (2010)
Martina Lundberg,
Louise Susan Harrington,
Phillip D.M. Leadbeater,
Tim D. Warner
and
Jane A. Mitchell
COX isoforms in aortic endothelial cells from young adult and mature adult mice. (2009)
M.H. Lundberg,
Louise Susan MacKenzie,
Ivana Vojnovic,
Timothy D. Warner
and
Jane A. Mitchell
Effect of COX-1 or COX-2 gene deletion on prostacyclin formation in the heart. (2009)
Philip DM Leadbeater,
Ivana Vojnovic,
Louise Susan MacKenzie,
Martina Lundberg,
Hime Gashaw,
Mark Paul-Clark,
Timothy D. Warner
and
Jane Mitchell
Relative expression of cyclo-oxygenase COX-1 and COX-2 in porcine endothelium subjected to chronic shear stress. (2009)
Claire M.F. Potter,
Martina H. Lundberg,
Louise Susan MacKenzie,
C.M. Warboys,
Hime Gashaw,
Timothy D. Warner,
P.D. Weinberg
and
Jane A. Mitchell
COX-1, and not COX-2 activity, regulates airway function : Relevance to aspirin-sensitive asthma. (2008)
L.S. Harrington,
R. Lucas,
S.K. McMaster,
L. Moreno,
G. Scadding,
J.A. Mitchell
and
T.D. Warner
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The PPAR target gene CD36 is a rate limiting factor for the sensing of gram positive S-aureus in vascular smooth muscle cells but not in macrophages. (2008)
L. Moreno,
S.K. McMaster,
M. Paul-Clark,
Louise Susan MacKenzie,
N. Cartwright,
T. Secher,
V. Quesniaux,
B. Ryffel
and
J.A. Mitchell
Evidence for a specific influence of the nitrergic pathway on the peripheral pulse waveform in rabbits. (2008)
B.A. Nier,
L.S. Harrington,
M.J. Carrier
and
P.D. Weinberg
Role of nitric oxide and prostacyclin as vasoactive hormones released by the endothelium. (2008)
J.A. Mitchell,
F. Ali,
L. Bailey,
L. Moreno
and
L.S. Harrington
Homeostatic role of toll-like receptor 4 in the endothelium and heart. (2007)
L.S. Harrington,
E. Belcher,
L. Moreno,
J.A. Mitchell
and
M.J. Carrier
Purinergic 2X receptors mediate endothelial dependent vasodilation to ATP. (2007)
L.S. Harrington,
F. Ali,
J.A. Mitchell,
J. Wray,
K.E. Swales,
L. Norling,
R.J. Evans,
C. Vial
and
M.J. Carrier
Elucidation of the temporal relationship between endothelial-derived NO and EDHF in mesenteric vessels. (2007)
L.S. Harrington,
J.A. Mitchell,
M.J. Carrier,
N. Gallagher,
C.J. Garland
and
D. Gilroy
Pharmacology of airways and vessels in lung slices in situ : Role of endogenous dilator hormones. (2006)
L. Moreno,
F. Perez-Vizcaino,
L. Harrington,
R. Faro,
G. Sturton,
P.J. Barnes
and
J.A. Mitchell
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Effects of Apamin and Charybdtoxin on Endothelium Independent Vasodilatation : Implications in the study of EDHF. (2005)
Louise Susan MacKenzie,
M.J. Carrier
and
J.A. Mitchell
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P2X receptors and the endothelium. (2005)
L.S. Harrington
and
J.A. Mitchell
Not so EEZE : the ‘EDHF’ antagonist 14, 15 Epoxyeicosa-5(z)-enoic Acid has vasodilator properties in mesenteric arteries. (2004)
Louise Susan MacKenzie,
John R. Falck
and
Jane A. Mitchell
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Novel role for P2X receptor activation in endothelium-dependent vasodilation. (2004)
L.S. Harrington
and
J.A. Mitchell
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The ‘EDHF’ Antagonist 14, 15 Epoxyeicosa-5(Z)-Enoic Acid has Vasodilator Properties in Mesenteric Vessels. (2004)
Louise Susan MacKenzie,
John R. Falck
and
Jane A. Mitchell
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The effects of organ culture on contractility and PLC delta 1 expression in rat mesenteric arteries. (2002)
Louise MacKenzie,
A.D. Hughes
and
Joanne Lymn
P-419: Phospholipase C isoforms and differentiation state of cultured human Vascular Smooth Muscle Cells. (2001)
Louise Susan MacKenzie,
C. Shelley,
M.K. Patel,
A.D. Hughes
and
Joanne Lymn
Co-ordinate regulation of metabolic enzyme encoding genes during cardiac development and following carvedilol therapy in spontaneously hypertensive rats. (2000)
Michael N. Sack,
Louise Harrington,
Anna K. Jonassen,
O.D. Mjos
and
Derek M. Yellon
PLC isoforms are associated with the differentiation status in human Vascular Smooth Muscle Cells. (2000)
Louise Susan Harrington,
C. Shelley,
Mahendra K. Patel,
Alun D. Hughes
and
Joanne Lymn
Refined Genetic Mapping of the Darier Locus to a <1-cM Region of Chromosome 12q24.1, and Construction of a Complete, High-Resolution P1 Artificial Chromosome/Bacterial Artificial Chromosome Contig of the Critical Region. (1998)
S. Monk,
A. Sakuntabhai,
R. Cox,
L. Harrington,
E. Levy,
M. Lathrop,
A.P. Monaco,
A. Hovnanian,
S. Burge,
S.A. Carter,
S.D. Bryce,
V.L. Ruiz-Perez,
E. Katsantoni,
A. Kodvawala,
T. Strachan,
J.L. Rees,
C.S. Munro,
M. Larrègue
and
G. Nagy