Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains : Structural insights based on similarity and molecular interaction fields

Drakulić, B.J., Stavri, M., Gibbons, S., Žižak, Ž.S., Verbić, T.Ž., Juranić, I.O. and Zloh, Mire (2009) Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains : Structural insights based on similarity and molecular interaction fields. ChemMedChem (12). pp. 1971-1975. ISSN 1860-7179
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(Chemical Equation Presented) Similar structure=similar activity? The effect of substituents on the antibacterial activity of aryldiketo acids has been rationalised by molecular interaction fields and similarity studies between investigated molecules and fluoroquinolone antibiotics.

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